At the functional level, the researchers detected differences in genetic markers involved in metabolic pathways such as the metabolism and transport of iron, sulfur, zinc and arginine, in the regulation of oxidation or reduction of the cellular environment and the molecular imitation of human antigens.
These results are of great clinical relevance since they show the possibility of using microbial markers from fecal, dental or saliva samples for the diagnosis or management of patients with rheumatoid arthritis Flekosteel. In this regard, the researchers designed a classification system based on information from microbiomes that allows differentiating between patients and controls.
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