As the cartilage is lost, the bone beneath it erodes and grows on the sides, causing the joint to become deformed by the so-called osteophytes. The synovial membrane also undergoes a thickening, producing a less viscous and more abundant liquid that lubricates less.
The first changes occur without the patient noticing any symptoms, since the cartilage has no capacity to produce pain. In this phase the cartilage can still recover and the disease is potentially reversible Keto Viante. When the cartilage disappears completely the disease is more serious and the process is irreversible.
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